Your gut isn’t just a tube for digesting food. It’s home to trillions of bacteria that:
• Help break down food
• Make key nutrients (like B vitamins)
• Train your immune system
• And — importantly — regulate estrogen levels
This bacterial community is called the gut microbiome, and when it’s healthy and diverse, it supports balanced hormones. But when the microbiome is out of balance — a condition called dysbiosis — problems can arise.
Inside the gut, a specific group of bacteria known as the estrobolome helps process estrogen. These bacteria produce enzymes (like beta-glucuronidase) that influence how much estrogen is reabsorbed into the bloodstream versus excreted.
When the estrobolome is overactive or underactive, it can lead to:
• Excess circulating estrogen → linked to endometriosis, fibroids, PMS, and breast tendernes
• Too little estrogen → contributing to mood changes, bone loss, and vaginal dryness
So a disrupted gut can directly amplify hormonal imbalances.
Both gut dysbiosis and endometriosis are associated with chronic inflammation. When the gut barrier is weakened (a condition sometimes called “leaky gut”), it allows inflammatory molecules to pass into the bloodstream. This triggers an immune response — and in people with endometriosis or PCOS, it can worsen pelvic pain, fatigue, and hormonal chaos.
While this field is still developing, early studies have found:
• Women with endometriosis often have altered gut microbiomes compared to those without the condition. [Study: Ata et al., 2019, Scientific Reports]
• A high-fiber, plant-rich diet may help support a more balanced gut flora and improve estrogen metabolism. [Study: Fuhrman et al., 2004, Journal of Nutrition]
• Some researchers are exploring probiotic therapy as a future tool for managing hormone-related conditions.
You can’t fully control your hormones — but you can support your gut.
Here are some gut-friendly, hormone-supporting habits:
• Eat more fiber: vegetables, fruits, legumes, and seeds
• Avoid excessive sugar and processed foods
• Include fermented foods: yogurt, kefir, sauerkraut, kimchi
• Consider a probiotic — talk to your provider first
• Manage stress — cortisol (the stress hormone) also affects gut balance
• Support liver detoxification (which works with your gut to clear estrogen): eat cruciferous vegetables like broccoli and cauliflower
The gut isn’t just about digestion — it’s a key player in how your body handles hormones, pain, and inflammation.
If you’re struggling with endometriosis, PCOS, or unexplained hormone symptoms, supporting your gut might be an empowering place to start.
Here are some helpful articles and research:
• The Gut Microbiome and Estrogen Metabolism – NIH
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471213/
• Gut Microbiota and Endometriosis – Scientific Reports
https://www.nature.com/articles/s41598-019-39645-2
• How the Gut Influences Hormones – Integrative Medicine Journal
Your gut isn’t just a tube for digesting food. It’s home to trillions of bacteria that:
• Help break down food
• Make key nutrients (like B vitamins)
• Train your immune system
• And — importantly — regulate estrogen levels
This bacterial community is called the gut microbiome, and when it’s healthy and diverse, it supports balanced hormones. But when the microbiome is out of balance — a condition called dysbiosis — problems can arise.
Inside the gut, a specific group of bacteria known as the estrobolome helps process estrogen. These bacteria produce enzymes (like beta-glucuronidase) that influence how much estrogen is reabsorbed into the bloodstream versus excreted.
When the estrobolome is overactive or underactive, it can lead to:
• Excess circulating estrogen → linked to endometriosis, fibroids, PMS, and breast tendernes
• Too little estrogen → contributing to mood changes, bone loss, and vaginal dryness
So a disrupted gut can directly amplify hormonal imbalances.
Both gut dysbiosis and endometriosis are associated with chronic inflammation. When the gut barrier is weakened (a condition sometimes called “leaky gut”), it allows inflammatory molecules to pass into the bloodstream. This triggers an immune response — and in people with endometriosis or PCOS, it can worsen pelvic pain, fatigue, and hormonal chaos.
While this field is still developing, early studies have found:
• Women with endometriosis often have altered gut microbiomes compared to those without the condition. [Study: Ata et al., 2019, Scientific Reports]
• A high-fiber, plant-rich diet may help support a more balanced gut flora and improve estrogen metabolism. [Study: Fuhrman et al., 2004, Journal of Nutrition]
• Some researchers are exploring probiotic therapy as a future tool for managing hormone-related conditions.
You can’t fully control your hormones — but you can support your gut.
Here are some gut-friendly, hormone-supporting habits:
• Eat more fiber: vegetables, fruits, legumes, and seeds
• Avoid excessive sugar and processed foods
• Include fermented foods: yogurt, kefir, sauerkraut, kimchi
• Consider a probiotic — talk to your provider first
• Manage stress — cortisol (the stress hormone) also affects gut balance
• Support liver detoxification (which works with your gut to clear estrogen): eat cruciferous vegetables like broccoli and cauliflower
The gut isn’t just about digestion — it’s a key player in how your body handles hormones, pain, and inflammation.
If you’re struggling with endometriosis, PCOS, or unexplained hormone symptoms, supporting your gut might be an empowering place to start.
Here are some helpful articles and research:
• The Gut Microbiome and Estrogen Metabolism – NIH
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471213/
• Gut Microbiota and Endometriosis – Scientific Reports
https://www.nature.com/articles/s41598-019-39645-2
• How the Gut Influences Hormones – Integrative Medicine Journal
Your support can transform lives. Every donation helps us fund research, advocate for better care, and provide essential grants to women facing debilitating conditions.
Your support can transform lives. Every donation helps us fund research, advocate for better care, and provide essential grants to women facing debilitating conditions.
"I honestly can’t remember a time when my monthly cycles felt “normal.” From early on, they were always painful—something I learned to dread every single month. I had symptoms that I now know aren’t normal, but back then, I just assumed this was how it was supposed to be.
My symptoms affected both my physical and mental health. The abdominal pain and cramping would leave me doubled over, sometimes unable to move. I experienced nausea, vomiting, dizziness, and terrible headaches. But even more difficult were the days when anxiety took over so completely that the simple act of getting out of bed would trigger a panic attack. All I could do was lay there, waiting for the wave to pass, hoping I could eventually function at even the most basic level.
Over time, this pattern began to erode my daily life. I was told over and over again that I just had “bad cycles,” and that hormonal birth control was the only option. I tried it and quickly realized it wasn’t sustainable for me. The other response I often got was silence—or worse: “suck it up,” “push through it,” “this is just part of being a woman.” So I did what I thought I had to do: I learned to silently suffer, white-knuckling my way through each month.
By the time I reached my thirties, after having my two sweet kids, I only had about 5 or 6 days each month where I could carry out everyday tasks without pain or debilitating symptoms. I was barely making it through. That’s when I knew something had to change—I couldn’t keep living like this.
I hadn’t considered endometriosis until my twin sister, who had gone through very similar experiences, was diagnosed after several surgeries. Her story opened the door for me to seek answers of my own. With the support of a trusted doctor, I underwent testing. They suspected both endometriosis and adenomyosis.
A few months later, I had surgery. It confirmed both diagnoses. My uterus was removed due to adenomyosis, and endometriosis was also found and excised. That surgery gave me my life back. And I don’t say that lightly. For the first time in decades, I wasn’t confined to my bed. I didn’t have to plan my life around pain. I could move, breathe, think, and live. My kids had their mom back.
Some symptoms have returned in recent months, but this time I’m not doing it alone. I’m working closely with two practitioners—one addressing things holistically, the other exploring surgical options if needed. I feel supported, seen, and hopeful.
What I’ve learned through all of this is that far too many women are suffering in silence—dismissed, minimized, and left without answers. We’re told that this is just the way it is. But it doesn’t have to be.
That’s why I’m so incredibly grateful for Our Daughters Foundation and for people like Kara, who are bringing attention, support, and real solutions to parts of women’s health that have been ignored for far too long. Being told to “tough it out” leaves one feeling isolated. Knowing something’s wrong but not being sure if anyone will help you—that’s a different kind of pain.
Awareness changes that. Advocacy changes that. Community changes that.
Thank you, Our Daughters Foundation, for fighting for us—for helping women everywhere feel less alone, and for making it known that “just a bad period” is never something we should accept."
-Allie